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    Home»Bonds»Deoxygenative radical cross-coupling of C(sp3)−O/C(sp3)−H bonds promoted by hydrogen-bond interaction
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    Deoxygenative radical cross-coupling of C(sp3)−O/C(sp3)−H bonds promoted by hydrogen-bond interaction

    August 8, 2024


  • Ertl, P. & Schuhmann, T. A systematic cheminformatics analysis of functional groups occurring in natural products. J. Nat. Prod. 82, 1258–1263 (2019).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Dalton, T., Faber, T. & Glorius, F. C−H activation: toward sustainability and applications. ACS Cent. Sci. 7, 245–261 (2021).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Lam, N. Y. S., Wu, K. & Yu, J.-Q. Advancing the logic of chemical synthesis: C−H activation as strategic and tactical disconnections for C−C bond construction. Angew. Chem. Int. Ed. 133, 15901–15924 (2021).

    Article 
    ADS 

    Google Scholar
     

  • Boit, T. B., Bulger, A. S., Dander, J. E. & Garg, N. K. Activation of C−O and C−N bonds using non-precious metal catalysis. ACS Catal. 10, 12109–12126 (2020).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Choi, J. & Fu, G. C. Transition metal-catalyzed alkyl-alkyl bond formation: another dimension in cross-coupling chemistry. Science 356, No. eaaf7230 (2017).

    Article 
    PubMed 

    Google Scholar
     

  • Jana, R., Pathak, T. P. & Sigman, M. S. Advances in transition metal (Pd, Ni, Fe)-catalyzed cross-coupling reactions using alkyl-organometallics as reaction partners. Chem. Rev. 111, 1417–1492 (2011).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Johansson Seechurn, C. C. C., Kitching, M. O., Colacot, T. J. & Snieckus, V. Palladium-catalyzed cross-coupling: a historical contextual perspective to the 2010 Nobel prize. Angew. Chem. Int. Ed. 51, 5062–5085 (2012).

    Article 
    CAS 

    Google Scholar
     

  • Zhou, J. & Fu, G. C. Cross-couplings of unactivated secondary alkyl halides: room-temperature nickel-catalyzed Negishi reactions of alkyl bromides and iodides. J. Am. Chem. Soc. 125, 14726–14727 (2003).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Wang, Z., Yin, H. & Fu, G. C. Catalytic enantioconvergent coupling of secondary and tertiary electrophiles with olefins. Nature 563, 379–383 (2018).

    Article 
    ADS 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Huo, H., Gorsline, B. J. & Fu, G. C. Catalyst-controlled doubly enantioconvergent coupling of racemic alkyl nucleophiles and electrophiles. Science 367, 559–564 (2020).

    Article 
    ADS 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Giovannini, R., Stüdemann, T., Dussin, G. & Knochel, P. An efficient nickel-catalyzed cross-coupling between sp3 carbon centers. Angew. Chem. Int. Ed. 37, 2387–2390 (1998).

    Article 
    CAS 

    Google Scholar
     

  • Gao, Y., Zhang, B., He, J. & Baran, P. S. Ni-electrocatalytic enantioselective doubly decarboxylative C(sp3)–C(sp3) cross coupling. J. Am. Chem. Soc. 145, 11518–11523 (2023).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Zhang, B. et al. Complex molecule synthesis by electrocatalytic decarboxylative cross-coupling. Nature 623, 745–751 (2023).

    Article 
    ADS 
    CAS 
    PubMed 

    Google Scholar
     

  • Zhang, B. et al. Ni-electrocatalytic C(sp3)–C(sp3) doubly decarboxylative coupling. Nature 606, 313–318 (2022).

    Article 
    ADS 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Kang, K. & Weix, D. J. Nickel-catalyzed C(sp3)–C(sp3) cross-electrophile coupling of in situ generated NHP esters with unactivated alkyl bromides. Org. Lett. 24, 2853–2857 (2022).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Sun, D. & Doyle, A. G. Ni/Photoredox-catalyzed C(sp3)–C(sp3) coupling between aziridines and acetals as alcohol-derived alkyl radical precursors. J. Am. Chem. Soc. 144, 20067–20077 (2022).

    Article 

    Google Scholar
     

  • Hao, Y. et al. Nickel-catalyzed enantioconvergent reductive hydroalkylation of unactivated alkenes with α-pyridyl alkyl electrophiles. ACS Catal. 13, 15633–15640 (2023).

    Article 
    CAS 

    Google Scholar
     

  • Chen, M. & Montgomery, J. Nickel-catalyzed intermolecular enantioselective heteroaromatic C–H alkylation. ACS Catal. 12, 11015–11023 (2022).

    Article 

    Google Scholar
     

  • Canivet, J., Yamaguchi, J., Ban, I. & Itami, K. Nickel-catalyzed biaryl coupling of heteroarenes and aryl halides/triflates. Org. Lett. 11, 1733–1736 (2009).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • He, J., Wasa, M., Chan, K. S. L., Shao, Q. & Yu, J.-Q. Palladium-catalyzed transformations of alkyl C−H bonds. Chem. Rev. 117, 8754–8786 (2017).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Gandeepan, P. & Ackermann, L. Transient directing groups for transformative C−H activation by synergistic metal catalysis. Chem 4, 199–222 (2018).

    Article 
    CAS 

    Google Scholar
     

  • Sambiagio, C. et al. A comprehensive overview of directing groups applied in metal-catalyzed C–H functionalization chemistry. Chem. Soc. Rev. 47, 6603–6743 (2018).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Rej, S., Ano, Y. & Chatani, N. An efficient tool in C–H bond functionalization chemistry for the expedient construction of C–C bonds. Chem. Rev. 120, 1788–1887 (2020). Bidentate Directing Groups.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Chan, A. Y. et al. Metallaphotoredox: the merger of photoredox and transition metal catalysis. Chem. Rev. 122, 1485–1542 (2022).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Twilton, J. et al. The merger of transition metal and photocatalysis. Nat. Rev. Chem. 1, 0052 (2017).

    Article 
    CAS 

    Google Scholar
     

  • Shaw, M. H., Shurtleff, V. W., Terrett, J. A., Cuthbertson, J. D. & MacMillan, D. W. C. Native functionality in triple catalytic cross-coupling: sp3 C–H bonds as latent nucleophiles. Science 352, 1304–1308 (2016).

    Article 
    ADS 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Le, C., Liang, Y., Evans, R. W., Li, X. & MacMillan, D. W. C. Selective sp3 C–H alkylation via polarity-match-based cross-coupling. Nature 547, 79–83 (2017).

    Article 
    ADS 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Perry, I. B. et al. Direct arylation of strong aliphatic C–H bonds. Nature 560, 70–75 (2018).

    Article 
    ADS 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Che, C., Lu, Y.-N. & Wang, C.-J. Enantio- and diastereoselective De Novo synthesis of 3‑substituted proline derivatives via cooperative photoredox/Brønsted acid catalysis and epimerization. J. Am. Chem. Soc. 145, 2779–2786 (2023).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Che, C., Li, Y.-N., Cheng, X., Lu, Y.-N. & Wang, C.-J. Visible-light-enabled enantioconvergent synthesis of α-amino acid derivatives via synergistic Brønsted acid/photoredox catalysis. Angew. Chem. Int. Ed. 60, 4698–4704 (2021).

    Article 
    CAS 

    Google Scholar
     

  • Yang, L. et al. Molecular oxygen-mediated radical alkylation of C(sp3)−H bonds with boronic acids. Org. Lett. 23, 3207–3210 (2021).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Wang, Z.-H. et al. TEMPO-enabled electrochemical enantioselective oxidative coupling of secondary acyclic amines with ketones. J. Am. Chem. Soc. 143, 15599–15605 (2021).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Salman, M., Zhu, Z.-Q. & Huang, Z.-Z. Dehydrogenative cross-coupling reaction between N‑aryl α‑amino acid esters and phenols or phenol derivative for synthesis of α‑aryl α‑amino acid esters. Org. Lett. 18, 1526–1529 (2016).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Gao, X.-W. et al. Visible light catalysis assisted site-specific functionalization of amino acid derivatives by C−H bond activation without oxidant: cross-coupling hydrogen evolution reaction. ACS Catal. 5, 2391–2396 (2015).

    Article 
    CAS 

    Google Scholar
     

  • Zhang, G., Zhang, Y. & Wang, R. Catalytic asymmetric activation of a C(sp3)−H bond adjacent to a nitrogen atom: a versatile approach to optically active α-alkyl α-amino acids and C1-alkylated tetrahydroisoquinoline derivatives. Angew. Chem. Int. Ed. 50, 10429–10432 (2011).

    Article 
    CAS 

    Google Scholar
     

  • Zhao, L. & Li, C.-J. Functionalizing glycine derivatives by direct C–C bond formation. Angew. Chem. Int. Ed. 47, 7075–7078 (2008).

    Article 
    CAS 

    Google Scholar
     

  • Qiu, Z. & Li, C.-J. Transformations of less-activated phenols and phenol derivatives via C–O cleavage. Chem. Rev. 120, 10454–10515 (2020).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Komeyama, K., Michiyuki, T. & Osaka, I. Nickel/Cobalt-catalyzed C(sp3)–C(sp3) cross-coupling of alkyl halides with alkyl tosylates. ACS Catal. 9, 9285–9291 (2019).

    Article 
    CAS 

    Google Scholar
     

  • Liu, J.-H. et al. Copper-catalyzed reductive cross-coupling of nonactivated alkyl tosylates and mesylates with alkyl and aryl bromides. Chemistry 20, 15334–15338 (2014).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Greene, M. A., Yonova, I. M., Williams, F. J. & Jarvo, E. R. Traceless directing group for stereospecific nickel-catalyzed alkyl-alkyl cross-coupling reactions. Org. Lett. 14, 4293–4296 (2012).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Wisniewska, H. M., Swift, E. C. & Jarvo, E. R. Functional-group-tolerant, nickel-catalyzed cross-coupling reaction for enantioselective construction of tertiary methyl-bearing stereocenters. J. Am. Chem. Soc. 135, 9083–9090 (2013).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Chen, H.-W. et al. Asymmetric deoxygenative cyanation of benzyl alcohols enabled by synergistic photoredox and copper catalysis. Chin. J. Chem. 38, 1671–1675 (2020).

    Article 
    ADS 
    CAS 

    Google Scholar
     

  • Lu, F.-D. et al. Asymmetric propargylic radical cyanation enabled by dual organophotoredox and copper catalysis. J. Am. Chem. Soc. 141, 6167–6172 (2019).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Sakai, A. & MacMillan, D. W. C. Nontraditional fragment couplings of alcohols and carboxylic acids: C(sp3)–C(sp3) cross-coupling via radical sorting. J. Am. Chem. Soc. 144, 6185–6192 (2022).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Dong, Z. & MacMillan, D. W. C. Metallaphotoredox-enabled deoxygenative arylation of alcohols. Nature 598, 451–456 (2021).

    Article 
    ADS 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Lyon, W. L. & MacMillan, D. W. C. Expedient access to underexplored chemical space: deoxygenative C(sp3)–C(sp3) cross-coupling. J. Am. Chem. Soc. 145, 7736–7742 (2023).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Intermaggio, N. E., Millet, A., Davis, D. L. & MacMillan, D. W. C. Deoxytrifluoromethylation of alcohols. J. Am. Chem. Soc. 144, 11961–11968 (2022).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Schäfer, S. et al. Pyridylalanine-containing hydroxamic acids as selective HDAC6 inhibitors. ChemMedChem 4, 283–290 (2009).

    Article 
    PubMed 

    Google Scholar
     

  • Mulliken, R. S. Molecular compounds and their spectra. III. The interaction of electron donors and acceptors. J. Phys. Chem. 56, 801–822 (1952).

    Article 
    CAS 

    Google Scholar
     

  • Rosokha, S. V. & Kochi, J. K. Fresh look at electron-transfer mechanisms via the donor/acceptor bindings in the critical encounter complex. Acc. Chem. Res. 41, 641–653 (2008).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • de Lima, C. G. S. M., Lima, T., Duarte, M., Jurberg, I. D. & Paixão, M. W. Organic synthesis enabled by light-irradiation of EDA complexes: theoretical background and synthetic applications. ACS Catal. 6, 1389–1407 (2016).

    Article 
    CAS 

    Google Scholar
     



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